Professor

Prof Kirsty Le Doare

Professor Le Doare joined the SGUL from Imperial College London in September 2018 as part of the Paediatric Infectious Diseases Research Group. She trained as a clinician-scientist in Paediatric Infectious Diseases in the UK, the Gambia and South Africa. Kirsty holds a Chair in Vaccinology and Immunology and is a Principal Scientist at MRC/UVRI@LSHTM in Uganda where she is developing a maternal vaccine platform and surveillance of pregnancy outcomes in a large urban cohort. She was awarded a UKRI Future Leaders Fellowship in 2019.

In the UK and in Uganda her main research interests are age-related immune responses to infectious diseases in pregnant women and their babies. She is interested in improving our knowledge of how maternal antibody in blood and breast milk is passed to babies and how this protects them from colonisation and disease and how we might improve this with vaccination. Her group leads several clinical trials of investigative vaccines in Uganda.

Professor Le Doare is jointly appointed to Public Health England as a principal scientist with the Pathogen Immunity Group, Porton Down.

Operations Manager

Madeleine Cochet

Madeleine is Operations Manager for Prof. Kirsty Le Doare in the CNPI. Madeleine holds an MSc in Public Health from London School of Hygiene and Tropical Medicine, and a BSc in Microbiology from the University of Massachusetts, Amherst. Madeleine’s research interest is determinants of health and infectious diseases. Her previous experience has provided her with a strong foundation in clinical research, with a focus in project management.

Honorary staff

Joseph Peacock

Joseph supports the project management of a range of Prof Le Doare’s studies at the CNPI across both the UK and Uganda. His role involves supporting the delivery of ongoing neonatal and paediatric research by monitoring research activity, working with research practitioners across a large range of sites to ensure compliance with regulatory requirements and Good Clinical Practice, and liaising with a range of external partners and international collaborators. He also supports researchers throughout the timeline of clinical research, from the preparation of grant applications to the publication of research outputs.

Joseph also serves as a member of the Animal Welfare and Ethical Review Body (AWERB) for St George’s, University of London, and participates in the University’s Environmental Working Group.

Joseph recently completed an MSc in Medical Anthropology at UCL. His research interests include risk perception in relation to vaccination, outbreak events and emerging infectious disease threats, as well as attitudes to vaccination, infection and trial participation.

Tom Hall

Tom’s work within the Le Doare lab involves using serological assays (ELISA and multiplex immunoassays) to measure antibody responses to neonatal infectious diseases, such as Group B Streptococcus (GBS) and B. pertussis.

Tom’s role is to manage the laboratory to ensure a smooth process from sample reception to antibody testing and result reporting. He also leads on the development of new antibody tests.

Tom’s general interests include the use of serological assays and their application to disease epidemiology and vaccine development. He has previously worked in pneumococcal vaccine trials, malaria epidemiology, and Ebola diagnostics.

Research Scientist

Olwenn Daniel

Olwenn joined the lab team of Prof Kirsty Le Doare in 2020 as a technician, after completing a Master in Infectiology (Lyon I).

Olwenn’s current work on Group B Streptococcus and Bordetella pertussis involves the development of immunological assays for antibody measurement, the quality control of results, and data analysis.

Honorary Staff

Dr Hannah Davies

Hannah’s background is in clinical medicine, she specialises in paediatrics with an interest in surveillance of infectious diseases, particularly those that occur in the perinatal period. Hannah’s clinical experience has been divided between the UK and Africa, where she is currently the study coordinator for the ProGreSs study – a large cohort study of mothers and infants based in Kampala, Uganda, that aims to determine the levels of protective antibody against Group B Streptococcus that are passed from mothers to their babies during pregnancy, comparing antibody levels in babies.

Hannah is currently developing a proposal for a higher degree in clinical epidemiology.

Clinical Research Fellow

Dr Kostas Karampatsas

Kostas is a senior paediatric trainee, working clinically at St George’s Hospital, London. Kostas graduated from Aristotle University of Thessaloniki in 2007 and finished his MA in Anthropology of Body and Health at Goldsmiths College, University of London in 2010. Currently, Kostas is a Clinical Research Fellow working with the Paediatric Infectious Diseases Research Group in St. George’s University of London on projects around maternal immunisation. He is particularly interested in exploring the potential of maternal immunization as a feasible and accessible strategy to improve global health.

Clinical Research Fellow

Dr Eve Nakabembe

Academic Clinical Lecturer

Dr Nuria Sanchez Clemente

Dr Sanchez Clemente is a paediatric registrar and NIHR Academic Clinical Lecturer in paediatric infection and immunity at St. George’s University, London. Her academic and clinical interests are around congenital infections, neglected tropical diseases, health inequalities and migrant health.

In 2010, as part of an MSc in Tropical Medicine (LSHTM) Dr Sanchez Clemente travelled to the Peruvian Andes to undertake the first systematic review on Peruvian Bartonellosis. From 2014-2017, while living in Brazil, she did a PhD on congenital Zika syndrome, studying the perinatal outcomes of a Zika pregnancy cohort in the state of Sao Paulo. Since then, she has continued to work with teams in Brazil as well as the LSHTM and WHO to study the long term consequences for children born with congenital Zika infection and the wider impacts on their families and societies.

Dr Sanchez Clemente’s more recent academic and clinical interests are around migrant health and health inequalities, and she is studying large primary care datasets in order to compare patterns of paediatric primary and secondary healthcare usage between migrants and non-migrants in the UK. As a volunteer with Doctors of the World, Dr Sanchez Clemente has also been analysing maternal and postnatal outcomes of undocumented migrants in the UK. In the last year she has also been working on the ‘Respond’ Refugee Family Project at UCLH, which has involved qualitative research and the design of pathways for newly arrived asylum seeking children and young people to better understand and meet their needs in terms of infectious disease screening, mental health assessments, and safeguarding.

During her ACL, Dr Sanchez Clemente also plans to work with the UKHSA to study current patterns of COVID and primary immunisation uptake in the UK by deprivation index and ethnicity.

Honorary staff

Dr Sarah Sturrock

Dr Sturrock is an Academic Clinical Fellow and paediatric trainee working with Prof Le Doare’s team. Her current projects include the periCOVID study, looking at seroepidemiology, antibody transfer and neonatal outcomes following maternal COVID-19 infection in pregnancy, as well as the NeoMiniGut study of neonatal gut organoids.

Clinical Trials Manager

Dr Mary Kyohere

A Ugandan trained medical doctor, holding an MSc Global Health from University College London, with over a decade of experience working in, coordinating and managing clinical research studies in communities and health facilities in low resource settings. I have also been involved in public health engagement projects aimed at promoting maternal vaccination among women of child-bearing age and knowledge of COVID-19 spread and prevention among primary school aged children. 

Currently managing the iGBS3 study, that seeks to provide evidence that the relationship between an immune marker value (anti-GBS IgG concentration) and the probability of invasive GBS (iGBS) disease in infants less than 90 days of age is sufficiently strong that a vaccine able to induce an immune response will lead to a meaningful decrease in the probability of iGBS disease. 

Affiliations:  

• Makerere University Johns Hopkins University (MUJHU) Care Ltd| MUJHU Research Collaboration 
• IMPRINT Network

Clinical Study Manager

Sophie Bowlzer-Astick

Sophie is a Clinical Study Manager in Prof Kirsty Le Doare’s team in the CNPI. She holds a BSc in Neuroscience from UCL, and an MSc in Biomedical Sciences from KU Leuven. Sophie has a background in early phase clinical research in both academic and commercial settings, and has worked in diabetes, HIV and oncology research. She is currently working on the PROTECT and PREPARE studies.

Academic Clinical Lecturer

Dr Rosie Crane

Dr Rosie Crane is a Clinical Lecturer whose research aims to reduce the morbidity and mortality burden of infectious disease amongst infants and children in global settings. Rosie’s current research investigates the possible role of breastfeeding and human breastmilk constituents in prevention of enteric colonisation with antimicrobial-resistant bacteria amongst infants.

Research Scientist

Emily Bentley

Emily joined the lab team in 2023 as a laboratory technician, and her current work on Group B Streptococcus involves serological testing and assay development. Prior to joining the group, Emily completed a BSc in Medical Sciences and worked in assay development for lateral flow diagnostics.

Clinical Trials Manager

Stacy Mbabazi

Senior Clinical Research Fellow

Andrew Young

Andy is a consultant paediatrician and clinical researcher with experience in general paediatrics, paediatric respiratory medicine and paediatric global health. He works across clinical, academic and public health settings, with roles at St George’s University Hospital, and City St George’s, University of London. His research focuses on group B Streptococcus, RSV, maternal immunisation and surveillance systems to improve outcomes for infants and children. He has experience in clinical trials, epidemiology, guideline development, governance and teaching, including work in Uganda, Malawi and Sierra Leone.